Luigi Orrù

Consiglio per la Ricerca e la Sperimentazione in Agricoltura
Genomics Research Centre
via S. Protaso, 302
I -29017 Fiorenzuola d'Arda PC, Italy

Curriculum vitae
March 2008 – present. Permanent position as researcher at CRA-Genomic Research Centre – Fiorenzuola d’Arda.
From 2003 to 2008 Researcher (temporary position) at Istituto Sperimentale per la Zootecnia – Monterotondo (Roma) (CRA) working on identification of genetic markers for productive and quality traits in farm animals.
2000-2002. A Telethon grant related to the project "" Altered bone cell function in osteopetrosis"" at University of L’Aquila- Department of Experimental Medicine
1997-2000. PhD in Molecular and Cellular Pharmacology at the University of Rome “La Sapienza”, Institute of Medical Pharmacology.
1995. Bachelor of Biology at the University of Rome “La Sapienza”, Department of Cellular Biotechnologies and Hematology

Current research interests
Luigi Orrù is a molecular biologist, his expertise lies in the application of Illumina massively parallel sequencing technology in the analysis of genomes and gene expression. His work is mainly focused on the analysis of microbial genomes.

Selected recent publications

  1. Lamontanara A., Orrù L., Cattivelli L., Russo P., Spano G., Capozzi V. (2014). Genome sequence of Oenococcus oeni OM27, the first fully assembled genome of a strain isolated from an Italian wine. Genome Announc 2(4): e00658-14
  2. Capozzi V., Russo P., Lamontanara A., Orrù L., Cattivelli L., Spano G. (2014). Genome sequenze off five Oenococcus oeni strains isolated from Nero di Troia wine from the same terroir in Apulia, southern Italy. Genome Announc 2(5):e01077-14. doi:10.1128/genomeA.01077-14.
    Orrù L., Salvetti E., Cattivelli L., Lamontanara A., Michelotti V., Capozzi V., Spano G., Keller D., Cash H., Martina A., Torriani S., Felis GE. (2014). Draft genome sequence of Bacillus coagulans GBI-30, 6086, a widely used spore-forming prebiotico strain. Genome Announc 2(6):e01080-14. doi:10.1128/genomeA.01080-14
  3. Aragona M., Minio A., Ferrarini A., Valente MT., Bagnaresi P., Orrù L., Tononi P., Zamperin G., Infantino A., Valè G., Cattivelli L. and Delledonne M. (2014). De novo genome assembly of the soil-borne fungus and tomato pathogen Pyrenochaeta lycopersici. BMC Genomics 2014, 15:313 doi:10.1186/1471-2164-15-313
  4. Bagnaresi P., Biselli C., Orrù L., Urso S., Crispino L., Abbruscato P., Piffanelli P., Lupotto E., Cattivelli L., Valè G. (2012). Comparative transcriptome profiling of the early response to Magnaporthe oryzae in durable resistant vs susceptible rice (Oryza sativa L.) genotypes. PLoS ONE. 7(12): e51609. doi:10.1371/journal.pone.0051609
  5. Colaiacovo M, Bernardo L, Centomani I, Crosatti C, Giusti L, Orrù L, Tacconi G, Lamontanara A, Cattivelli L and Faccioli P. (2012). A survey of microRNA length variants contributing to miRNome complexity in peach (Prunus persica L.). Front. Plant Sci. 3:165. doi: 10.3389/fpls.2012.00165
  6. Orrù L., Abeni F., Gennaro C., Grandoni F., Crisà A., De Matteis G., Scatà MC., Napolitano F., Moioli B. (2012). Leptin gene haplotypes are associated with change in immunological and hematological parameters in dairy cow during the peripartum period. Journal of Animal Science. 90(1): 16-26. doi:10.2527/jas.2010-3706
  7. Rizza F., Pagani D., Gut M., Prasil IT., Lago C., Tondelli A., Orrù L., Mazzucotelli E., Francia E., Badeck FW., Crosatti C., Terzi V., Cattivelli L., Stanca AM. (2011). Diversity in the response to low temperature in representative barley genotypes cultivated in Europe. Crop Science. 51(6): 2759-2779 doi:10.2135/cropsci2011.01.0005
  8. Orrù L., Cifuni GF., Piasantier E., Corazzin M., Bovolenta S., Moioli B. (2011). Association analyses of single nucleotide polymorphisms in the Lep and SCD1 genes on the fatty acid profile of muscle fat in Simmental bulls. Meat Science 87:344-348
  9. Piasentier E., Bovolenta S., Moioli B., Orrù L., Valusso R., Corazzin M. (2009). Fatty acid composition and sensory properties of Italian Simmental beef as affected by genes frequency of Montbéliarde origin. Meat Science 83:543-550. doi:10.1016/j.meatsci.2009.07.003.
  10. Signorelli F., Orrù L., Napolitano F., De Matteis G., Scatà MC., Catillo G., Marchitelli C. and Moioli B. (2009). Exploring polymorphisms and effects on milk traits of the DGAT1, SCD1 and GHR genes in four cattle breeds. Livestock Science. 125:74-79 doi:10.1016/j.livsci.2009.02.014
  11. Orrù L., Catillo G., Napolitano F., De Matteis G., Scatà MC., Signorelli F. and Moioli B. (2009). Characterization of a SNPs panel for meat traceability in six cattle breeds. Food Control. 20:856-860. doi:10.1016/j.foodcont.2008.10.015
  12. Signorelli F., Contarini G., Annichiarico G., Napolitano F., Orrù L., Catillo G., Haenlein GFW. and Moioli B. (2008). Breed differences in sheep milk fatty acid profiles: Opportunities for sustainable use of animal genetic resources. Small Ruminant Research. 78: 24-31
  13. Moioli B., Contarini G., Avalli A., Catillo G., Orrù L., De Matteis G., Masoero G. and Napolitano F. (2007). Short comunication: Effect of stearoyl-Coenzyme A Desaturase polymorphism on fatty acid composition of milk. J. Dairy Sci. 90: 3553-3558
  14. Moioli B., Napolitano F., Orrù L. and Catillo G. (2006). Analysis of the genetic diversity between Gentile di Puglia, Sopravissana and Sarda sheep breeds using microsatellite markers. Italian Journal of Animal Science. 5:73-78.
  15. Orrù L., Napolitano F., Catillo G. and Moioli B. (2006). Meat molecular traceability: How to choose the best set of microsatellites? Meat Science. 72: 312-317.
  16. Moioli B., Napolitano F., Orrù L. and Catillo G. (2005). Single nucleotide polymorphism detection in promoter III of the acetyl-CoA carboxylase-? gene in sheep. Journal of Animal Breeding and Genetics. 122: 418-420.
  17. Rucci N., Di Giacinto C., Orrù L., Millimaggi D., Baron R. and Teti A. (2005). A novel protein kinase C a-dependent signal to ERK 1/2 activated by avb3 integrin in osteoclast and in Chinese hamster ovary (CHO) cells. Journal of Cells Science. 118(15): 3263-3275.
  18. Perez M., Migliaccio S., Taranta A., Festuccia C., Orrù L., Brama M., Bologna M., Faraggiana T., Baron R. and Teti A. (2001). Melanome cells stimulate osteoclastogenesis, c-Src expression and osteoblast cytokines. European Journal Cancer. 37(5):629-40
  19. Fuso A., Cavallaro R.A., Orrù L., Buttarelli F.R. and Scarpa S. (2001). Gene silencing by S-adenosylmethionine in muscle differentiation. FEBS Lett. 508(3): 337-40.
  20. Scarpa S., Narzi L., Lucarelli M., Orrù L. and Strom R. (2001). Erythroid differentiation and regulatory gene expression are modulated by adenosine derivatives interfering with S-adenosylmethionine metabolic pathway. Journal of Cell Biochemistry 81(3):401-12.
  21. Negri L., Lattanzi R., Tabacco F., Orrù L., Severini C., Scolaro B. and Rocchi R. (1999). Dermorphin and Deltorphin glycosylated analogues: syntesis and antinociceptive activity after systemic administration. Journal of Medicinal Chemistry. 42(3):400-404


The Genomics Research Centre holds a collection of more than one hundred barley mutants.

Our contacts

Genomics Research Centre
Via S. Protaso, 302
29017 Fiorenzuola d'Arda (PC) - ITALY
+39 0523 983758
+39 0523 983750
How to find us

We thank Renzo Alberici, Donata Pagani and Gianni Tacconi for setting up the picture collection.