Delfina Barabaschi



Consiglio per la Ricerca e la Sperimentazione in Agricoltura
Genomics Research Centre
via S. Protaso, 302
I -29017 Fiorenzuola d'Arda PC, Italy
delfina.barabaschi@crea.gov.it


Curriculum vitae
2002, Master's Degree in Biological sciences, University of Parma (Italy). Thesis Title “Stress ipertonico ed espressione di ATA2 in fibroblasti umani in coltura”
2007, PhD in Agronomic Biotechnology, University of Modena and Reggio Emilia (Italy). Thesis Title “Survey of molecular diversity at nud locus in barley”
2007, Internship at Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Department Genebank, Gatersleben (Germany). Topic “Physical mapping of the barley Fr-H2 (Frost resistance-H2) locus”
2010, Post-Doc Researcher Position at CRA - Genomics Research Centre

Current research interests
Since 2009 my work has been mainly focused on the genetic and genomic analysis of bread wheat.
I was involved in the “Physical mapping of wheat chromosome 5A” project from 2009 to 2014, in the frame of the International Wheat Genome Sequence Consortium.
To develop a high quality physical map of 5A, based on two fingerprinted arm-specific BAC libraries, we combined two assembly tools and several anchoring approaches based on PCR marker screening, microarray and BlastN searches, applied to interlinked genomic tools, i.e. genetic maps, deletion bin map, high-density neighbor map, BAC end sequences, genome zipper and chromosome survey sequences. Comparative analysis between the gene distribution along the wheat chromosome 5A and the closest related genomes showed a pattern of syntenic blocks belonging to different chromosomes of Brachypodium, rice and sorghum and regions involving translocations and inversions. The physical map produced thanks to this project is currently the most comprehensive map for 5A chromosome: an essential resource for fine genetic mapping and map-based cloning of agronomically relevant traits, a reference for the 5A sequencing projects, and a fundamental step to gain insight of the evolutionary aspects of bread wheat.
In the frame of the "Canadair" project, a bi-lateral project Italia-Canada, and in collaboration with the group of Hermann Buerstmayr of the Institute for Biotechnology in Plant Production (IFA-Tulln), Austria, I'm working on the genetic and physical analysis of the Fusarium head blight resistance locus on chromosome 5A in bread wheat, employing the genomic resources developed in the “Physical mapping of wheat chromosome 5A” project and moreover exploiting a panel of radiation hybrid lines developed in the reference cultivar Chine spring and specific for 5A chromosome.
I’m also involved in a genome-wide association study for spike traits in an Italian bread wheat collection in collaboration with Research Unit for Cereal Selection in Continental Areas (CRA-SCV), Sant’Angelo Lodigiano (LO, Italy), aimed to dissect these quantitative traits at the genetic levels and to develop molecular markers useful in assisted breeding.

Selected recent publications

  1. Tondelli A, Francia E, Barabaschi D, Aprile A, Skinner JS, Stockinger EJ, Stanca AM and Pecchioni N (2006) Mapping regulatory genes as candidates for cold and drought stress tolerance in barley. Theoretical and Applied Genetics. 112: 445-454.
  2. Barabaschi D, Campani L, Francia E, Toubia-Rahme H, Valé GP, Gianinetti A, Delogu G, Stanca A M and Pecchioni N (2007) Haplotype structure around the nud locus in barley and its association with resistance to leaf stripe (Pyrenophora graminea). Plant Breeding. 126: 24-29.
  3. Francia E, Barabaschi D, Tondelli A, Laidò G, Rizza F, Stanca AM, Busconi M, Fogher C, Stockinger EJ and Pecchioni N (2007) Fine mapping of a HvCBF gene cluster at the frost resistance locus Fr-H2 in barley. Theoretical and Applied Genetics. 115: 1083-1091.
  4. Laidò G, Barabaschi D, Gianinetti A, Stanca AM, Paoletta G, Li Destri Nicosia, O, Di Fonzo N, Francia E and Pecchioni N (2008) QTL alleles from a winter feed type can improve malting quality in barley. Plant Breeding. 128(6): 598-605.
  5. Tondelli A, Francia E, Barabaschi D, Pasquariello M and Pecchioni N (2011) Inside the CBF locus in Poaceae. Plant Science. 180: 39-45.
  6. Barabaschi D, Guerra D, Lacrima K, Laino P, Michelotti V, Urso S, Valè G and Cattivelli L (2012) Emerging Knowledge from Genome Sequencing of Crop Species (Review Article). Molecular Biotechnology. 50(3): 250-266.
  7. Barabaschi D, Francia E, Tondelli A, Gianinetti A, Stanca AM, Pecchioni N (2012) Effect of the nud Gene on Grain Yield in Barley. Czech Journal of Genetics and Plant Breeding 48(1): 10-22.
  8. Pasquariello M, Barabaschi D, Himmelbach A, Steuernagel B, Ariyadasa R, Stein N, Gandolfi F, Tenedini E, Bernardis I, Tagliafico E, Pecchioni N, Francia E (2014) The barley Frost resistance-H2 locus. Functional & Integrative Genomics. 14(1): 85-100.
  9. Borrelli G, Orrù L, De Vita P, Barabaschi D, Mastrangelo AM, Cattivelli L (2014) Integrated views in plant breeding: from the perspective of biotechnology. In: Victor O. Sadras and Daniel Calderini, editors: Crop Physiology, Oxford: Academic Press. p. 467-486.
  10. Barabaschi D, Magni F, Volante A, Gadaleta A, Šimková H, Scalabrin S, Prazzoli ML, Bagnaresi P, Lacrima K, Michelotti V, Desiderio F, Orrù L, Francia E, Fricano A, Mastrangelo AM, Tononi P, Vitulo N, Jurman I, Frenkel Z, Cattonaro F, Morgante M, Blanco A, Doležel J, Delledonne M, Stanca AM, Cattivelli L, Valè G (2015) Physical mapping of bread wheat chromosome 5A: an integrated approach. submitted

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The Genomics Research Centre holds a collection of more than one hundred barley mutants.

Our contacts

Genomics Research Centre
Via S. Protaso, 302
29017 Fiorenzuola d'Arda (PC) - ITALY
Phone:
+39 0523 983758
Fax:
+39 0523 983750
E-mail:
gpg@entecra.it
How to find us

We thank Renzo Alberici, Donata Pagani and Gianni Tacconi for setting up the picture collection.